Mucin O-glycans are natural inhibitors of Candida albicans pathogenicity

Mucins are large gel-forming polymers inside the mucus barrier that inhibit the yeast to hyphal transition of Candida albicans, a key virulence trait of this important human fungal pathogen. However, the molecular motifs in mucins that inhibit filamentation remain unclear, despite their potential fo...

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Detalhes bibliográficos
Publicado no:Nat Chem Biol
Main Authors: Takagi, Julie, Aoki, Kazuhiro, Turner, Bradley S., Lamont, Sabrina, Lehoux, Sylvain, Kavanaugh, Nicole, Gulati, Megha, Arevalo, Ashley Valle, Lawrence, Travis J., Kim, Colin Y., Bakshi, Bhavya, Ishihara, Mayumi, Nobile, Clarissa J., Cummings, Richard D., Wozniak, Daniel, Tiemeyer, Michael, Hevey, Rachel, Ribbeck, Katharina
Formato: Artigo
Idioma:Inglês
Publicado em: 2022
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7613833/
https://ncbi.nlm.nih.gov/pubmed/35668191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-022-01035-1
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