Mucin O-glycans are natural inhibitors of Candida albicans pathogenicity

Mucins are large gel-forming polymers inside the mucus barrier that inhibit the yeast to hyphal transition of Candida albicans, a key virulence trait of this important human fungal pathogen. However, the molecular motifs in mucins that inhibit filamentation remain unclear, despite their potential fo...

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Bibliografski detalji
Izdano u:Nat Chem Biol
Glavni autori: Takagi, Julie, Aoki, Kazuhiro, Turner, Bradley S., Lamont, Sabrina, Lehoux, Sylvain, Kavanaugh, Nicole, Gulati, Megha, Arevalo, Ashley Valle, Lawrence, Travis J., Kim, Colin Y., Bakshi, Bhavya, Ishihara, Mayumi, Nobile, Clarissa J., Cummings, Richard D., Wozniak, Daniel, Tiemeyer, Michael, Hevey, Rachel, Ribbeck, Katharina
Format: Artigo
Jezik:Inglês
Izdano: 2022
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7613833/
https://ncbi.nlm.nih.gov/pubmed/35668191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-022-01035-1
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