Mucin O-glycans are natural inhibitors of Candida albicans pathogenicity

Mucins are large gel-forming polymers inside the mucus barrier that inhibit the yeast to hyphal transition of Candida albicans, a key virulence trait of this important human fungal pathogen. However, the molecular motifs in mucins that inhibit filamentation remain unclear, despite their potential fo...

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Xehetasun bibliografikoak
Argitaratua izan da:Nat Chem Biol
Egile Nagusiak: Takagi, Julie, Aoki, Kazuhiro, Turner, Bradley S., Lamont, Sabrina, Lehoux, Sylvain, Kavanaugh, Nicole, Gulati, Megha, Arevalo, Ashley Valle, Lawrence, Travis J., Kim, Colin Y., Bakshi, Bhavya, Ishihara, Mayumi, Nobile, Clarissa J., Cummings, Richard D., Wozniak, Daniel, Tiemeyer, Michael, Hevey, Rachel, Ribbeck, Katharina
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2022
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7613833/
https://ncbi.nlm.nih.gov/pubmed/35668191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-022-01035-1
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