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Three-dimensional imaging mass cytometry for highly multiplexed molecular and cellular mapping of tissues and the tumor microenvironment

A holistic understanding of tissue and organ structure and function requires the detection of molecular constituents in their original three-dimensional (3D) context. Imaging mass cytometry (IMC) enables simultaneous detection of up to 40 antigens and transcripts using metal-tagged antibodies but ha...

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Bibliografiske detaljer
Udgivet i:Nat Cancer
Main Authors: Kuett, Laura, Catena, Raúl, Özcan, Alaz, Plüss, Alex, Schraml, Peter, Moch, Holger, de Souza, Natalie, Bodenmiller, Bernd
Format: Artigo
Sprog:Inglês
Udgivet: 2022
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7613779/
https://ncbi.nlm.nih.gov/pubmed/35121992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s43018-021-00301-w
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