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Multiplex Three-Dimensional Mapping of Macromolecular Drug Distribution in the Tumor Microenvironment

Macromolecular cancer drugs such as therapeutic antibodies and nanoparticles are well known to display slow extravasation and incomplete penetration into tumors, potentially protecting cancer cells from therapeutic effects. Conventional assays to track macromolecular drug delivery are poorly matched...

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Détails bibliographiques
Publié dans:Mol Cancer Ther
Auteurs principaux: Lee, Steve Seung-Young, Bindokas, Vytautas P., Kron, Stephen J.
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6318001/
https://ncbi.nlm.nih.gov/pubmed/30322947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-18-0554
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