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Hepatocellular carcinoma in Mongolia delineates unique molecular traits and a mutational signature associated with environmental agents

PURPOSE: Mongolia has the world’s highest incidence of hepatocellular carcinoma (HCC), with ˜100 cases/10(5) inhabitants, although the reasons for this feature have not been thoroughly delineated. EXPERIMENTAL DESIGN: We performed a molecular characterization of Mongolian (n=192) compared to Western...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Torrens, Laura, Puigvehí, Marc, Torres-Martín, Miguel, Wang, Huan, Maeda, Miho, Haber, Philipp K., Leonel, Thais, García-López, Mireia, Esteban-Fabró, Roger, Leow, Wei Qiang, Montironi, Carla, Torrecilla, Sara, Varadarajan, Ajay Ramakrishnan, Taik, Patricia, Campreciós, Genís, Enkhbold, Chinbold, Taivanbaatar, Erdenebileg, Yerbolat, Amankyeldi, Villanueva, Augusto, Pérez-del-Pulgar, Sofía, Thung, Swan, Chinburen, Jigjidsuren, Letouzé, Eric, Zucman-Rossi, Jessica, Uzilov, Andrew, Neely, Jaclyn, Forns, Xavier, Roayaie, Sasan, Sia, Daniela, Llovet, Josep M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2022
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7613712/
https://ncbi.nlm.nih.gov/pubmed/35998012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-22-0632
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