A functional microRNA screen uncovers O-linked N-acetylglucosamine transferase as a host factor modulating hepatitis C virus morphogenesis and infectivity

OBJECTIVE: Infection of human hepatocytes by the hepatitis C virus (HCV) is a multistep process involving both viral and host factors. microRNAs (miRNAs) are small non-coding RNAs that post-transcriptionally regulate gene expression. Given that miRNAs were indicated to regulate between 30% and 75% o...

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Publicado no:Gut
Main Authors: Herzog, Katharina, Bandiera, Simonetta, Pernot, Sophie, Fauvelle, Catherine, Jühling, Frank, Weiss, Amélie, Bull, Anne, Durand, Sarah C., Chane-Woon-Ming, Béatrice, Pfeffer, Sébastien, Mercey, Marion, Lerat, Hervé, Meunier, Jean-Christophe, Raffelsberger, Wolfgang, Brino, Laurent, Baumert, Thomas F., Zeisel, Mirjam B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7613422/
https://ncbi.nlm.nih.gov/pubmed/31076402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2018-317423
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