Transcriptomic signatures induced by the Ebola virus vaccine rVSVΔG-ZEBOV-GP in adult cohorts in Europe, Africa, and North America: a molecular biomarker study

BACKGROUND: A recombinant vesicular stomatitis virus vector expressing the Zaire Ebola virus glycoprotein (rVSVΔG-ZEBOV-GP) vaccine has been reported as safe, immunogenic, and highly protective in a ring vaccination trial. We aimed to identify transcriptomic immune response biomarker signatures indu...

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Published in:Lancet Microbe
Main Authors: Vianello, Eleonora, Gonzalez-Dias, Patricia, van Veen, Suzanne, Engele, Carmen G, Quinten, Edwin, Monath, Thomas P, Medaglini, Donata, Santoro, Francesco, Huttner, Angela, Dubey, Sheri, Eichberg, Michael, Ndungu, Francis M, Kremsner, Peter G, Essone, Paulin N, Agnandji, Selidji Todagbe, Siegrist, Claire-Anne, Nakaya, Helder I, Ottenhoff, Tom H M, Haks, Mariëlle C
Format: Artigo
Language:Inglês
Published: 2022
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7613316/
https://ncbi.nlm.nih.gov/pubmed/35544042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S2666-5247(21)00235-4
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