Clinical Immunology and Multiplex Biomarkers of Human Tuberculosis

Por Walzl, Gerhard, Haks, Mariëlle C., Joosten, Simone A., Kleynhans, Léanie, Ronacher, Katharina, Ottenhoff, Tom H.M.
Publicado no Cold Spring Harb Perspect Med (2015)

Human CD8(+) T-cells Recognizing Peptides from Mycobacterium tuberculosis (Mtb) Presented by HLA-E Have an Unorthodox Th2-like, Multifunctional, Mtb Inhibitory Phenotype and Repres...

Por van Meijgaarden, Krista E., Haks, Mariëlle C., Caccamo, Nadia, Dieli, Francesco, Ottenhoff, Tom H. M., Joosten, Simone A.
Publicado no PLoS Pathog (2015)

Impaired Immune Response to Primary but Not to Booster Vaccination Against Hepatitis B in Older Adults

Por Weinberger, Birgit, Haks, Mariëlle C., de Paus, Roelof A., Ottenhoff, Tom H. M., Bauer, Tanja, Grubeck-Loebenstein, Beatrix
Publicado no Front Immunol (2018)

Combination of gene expression patterns in whole blood discriminate between tuberculosis infection states

Por Mihret, Adane, Loxton, Andre G, Bekele, Yonas, Kaufmann, Stefan HE, Kidd, Martin, Haks, Mariëlle C, Ottenhoff, Tom HM, Aseffa, Abraham, Howe, Rawleigh, Walzl, Gerhard
Publicado em 2014

Cold acclimation affects immune composition in skeletal muscle of healthy lean subjects

Por van der Lans, Anouk A J J, Boon, Mariëtte R, Haks, Mariëlle C, Quinten, Edwin, Schaart, Gert, Ottenhoff, Tom H, van Marken Lichtenbelt, Wouter D
Publicado no Physiol Rep (2015)

Contributions of the T Cell Receptor–associated CD3γ–ITAM to Thymocyte Selection

Por Haks, Mariëlle C., Pépin, Elsa, van den Brakel, Jeroen H.N., Smeele, Sigrid A.A., Belkowski, Stanley M., Kessels, Helmut W.H.G., Krimpenfort, Paul, Kruisbeek, Ada M.
Publicado em 2002

Biomarkers Can Identify Pulmonary Tuberculosis in HIV-infected Drug Users Months Prior to Clinical Diagnosis

Por Sloot, Rosa, Schim van der Loeff, Maarten F., van Zwet, Erik W., Haks, Mariëlle C., Keizer, Sytze T., Scholing, Maarten, Ottenhoff, Tom H.M., Borgdorff, Martien W., Joosten, Simone A.
Publicado no EBioMedicine (2014)

BLR1 and FCGR1A transcripts in peripheral blood associate with the extent of intrathoracic tuberculosis in children and predict treatment outcome

Por Jenum, Synne, Bakken, Rasmus, Dhanasekaran, S., Mukherjee, Aparna, Lodha, Rakesh, Singh, Sarman, Singh, Varinder, Haks, Marielle C., Ottenhoff, Tom H. M., Kabra, S. K., Doherty, T. Mark, Ritz, Christian, Grewal, Harleen M. S.
Publicado no Sci Rep (2016)

Novel transcriptional signatures for sputum-independent diagnostics of tuberculosis in children

Por Gjøen, John Espen, Jenum, Synne, Sivakumaran, Dhanasekaran, Mukherjee, Aparna, Macaden, Ragini, Kabra, Sushil K., Lodha, Rakesh, Ottenhoff, Tom H. M., Haks, Marielle C., Doherty, Timothy Mark, Ritz, Christian, Grewal, Harleen M. S.
Publicado no Sci Rep (2017)

Combined chemical genetics and data-driven bioinformatics approach identifies receptor tyrosine kinase inhibitors as host-directed antimicrobials

Por Korbee, Cornelis J., Heemskerk, Matthias T., Kocev, Dragi, van Strijen, Elisabeth, Rabiee, Omid, Franken, Kees L. M. C., Wilson, Louis, Savage, Nigel D. L., Džeroski, Sašo, Haks, Mariëlle C., Ottenhoff, Tom H. M.
Publicado no Nat Commun (2018)

Identification of Probable Early-Onset Biomarkers for Tuberculosis Disease Progression

Por Sutherland, Jayne S., Hill, Philip C., Adetifa, Ifedayo M., de Jong, Bouke C., Donkor, Simon, Joosten, Simone A., Opmeer, Lizet, Haks, Marielle C., Ottenhoff, Tom H. M., Adegbola, Richard A., Ota, Martin O. C.
Publicado em 2011

Heterologous Protection against Malaria after Immunization with Plasmodium falciparum Sporozoites

Por Schats, Remko, Bijker, Else M., van Gemert, Geert-Jan, Graumans, Wouter, van de Vegte-Bolmer, Marga, van Lieshout, Lisette, Haks, Mariëlle C., Hermsen, Cornelus C., Scholzen, Anja, Visser, Leo G., Sauerwein, Robert W.
Publicado no PLoS One (2015)

Approaching a diagnostic point-of-care test for pediatric tuberculosis through evaluation of immune biomarkers across the clinical disease spectrum

Por Jenum, Synne, Dhanasekaran, S., Lodha, Rakesh, Mukherjee, Aparna, Kumar Saini, Deepak, Singh, Sarman, Singh, Varinder, Medigeshi, Guruprasad, Haks, Marielle C., Ottenhoff, Tom H. M., Doherty, Timothy Mark, Kabra, Sushil K., Ritz, Christian, Grewal, Harleen M. S.
Publicado no Sci Rep (2016)

Host Immune Responses Differ between M. africanum- and M. tuberculosis-Infected Patients following Standard Anti-tuberculosis Treatment

Por Tientcheu, Leopold D., Haks, Mariëlle C., Agbla, Schadrac C., Sutherland, Jayne S., Adetifa, Ifedayo M., Donkor, Simon, Quinten, Edwin, Daramy, Mohammed, Antonio, Martin, Kampmann, Beate, Ottenhoff, Tom H. M., Dockrell, Hazel M., Ota, Martin O.
Publicado no PLoS Negl Trop Dis (2016)

Molecular Signatures of Immunity and Immunogenicity in Infection and Vaccination

Por Haks, Mariëlle C., Bottazzi, Barbara, Cecchinato, Valentina, De Gregorio, Corinne, Del Giudice, Giuseppe, Kaufmann, Stefan H. E., Lanzavecchia, Antonio, Lewis, David J. M., Maertzdorf, Jeroen, Mantovani, Alberto, Sallusto, Federica, Sironi, Marina, Uguccioni, Mariagrazia, Ottenhoff, Tom H. M.
Publicado no Front Immunol (2017)

Transcriptomic evidence for modulation of host inflammatory responses during febrile Plasmodium falciparum malaria

Por Tran, Tuan M., Jones, Marcus B., Ongoiba, Aissata, Bijker, Else M., Schats, Remko, Venepally, Pratap, Skinner, Jeff, Doumbo, Safiatou, Quinten, Edwin, Visser, Leo G., Whalen, Elizabeth, Presnell, Scott, O’Connell, Elise M., Kayentao, Kassoum, Doumbo, Ogobara K., Chaussabel, Damien, Lorenzi, Hernan, Nutman, Thomas B., Ottenhoff, Tom H. M., Haks, Mariëlle C., Traore, Boubacar, Kirkness, Ewen F., Sauerwein, Robert W., Crompton, Peter D.
Publicado no Sci Rep (2016)