Mesp1 controls the chromatin and enhancer landscapes essential for spatiotemporal patterning of early cardiovascular progenitors

The mammalian heart arises from various populations of Mesp1-expressing cardiovascular progenitors (CPs) that are specified during the early stages of gastrulation. Mesp1 is a transcription factor (TF) that acts as a master regulator of CP specification and differentiation. However, how Mesp1 regula...

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Vydáno v:Nat Cell Biol
Hlavní autoři: Lin, Xionghui, Swedlund, Benjamin, Ton, Mai-Linh N., Ghazanfar, Shila, Guibentif, Carolina, Paulissen, Catherine, Baudelet, Elodie, Plaindoux, Elise, Achouri, Younes, Calonne, Emilie, Dubois, Christine, Mansfield, William, Zaffran, Stéphane, Marioni, John C., Fuks, Francois, Göttgens, Berthold, Lescroart, Fabienne, Blanpain, Cédric
Médium: Artigo
Jazyk:Inglês
Vydáno: 2022
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7613098/
https://ncbi.nlm.nih.gov/pubmed/35817961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-022-00947-3
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