Set-shifting related basal ganglia deformation as a novel familial marker of obsessive-compulsive disorder

The symptoms of obsessive-compulsive disorder (OCD) are suggestive of cognitive rigidity, and previous work identified impaired flexible responding on set-shifting tasks in such patients. The basal ganglia are central to habit learning, and are thought to be abnormal in OCD, contributing to inflexib...

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Publicado en:Br J Psychiatry
Autores principales: Isobe, Masanori, Vaghi, Matilde, Fineberg, Naomi A., Apergis-Schoute, Annemieke, Bullmore, Edward T, Sahakian, Barbara J., Robbins, Trevor W., Chamberlain, Samuel R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2022
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7613037/
https://ncbi.nlm.nih.gov/pubmed/35049465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1192/bjp.2021.45
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