Neural basis of impaired safety signaling in Obsessive Compulsive Disorder

The ability to assign safety to stimuli in the environment is integral to everyday functioning. A key brain region for this evaluation is the ventromedial prefrontal cortex (vmPFC). To investigate the importance of vmPFC safety signaling, we used neuroimaging of Pavlovian fear reversal, a paradigm t...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Apergis-Schoute, Annemieke M., Gillan, Claire M., Fineberg, Naomi A., Fernandez-Egea, Emilio, Sahakian, Barbara J., Robbins, Trevor W.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2017
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5373407/
https://ncbi.nlm.nih.gov/pubmed/28265059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1609194114
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