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Surface-tension-induced budding drives alveologenesis in human mammary gland organoids
Organ development involves complex shape transformations driven by active mechanical stresses that sculpt the growing tissue (1,2). Epithelial gland morphogenesis is a prominent example where cylindrical branches transform into spherical alveoli during growth(3–5). Here we show that this shape trans...
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| 發表在: | Nat Phys |
|---|---|
| Main Authors: | , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2021
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7612858/ https://ncbi.nlm.nih.gov/pubmed/35721781 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41567-021-01336-7 |
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