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Combining evidence from Mendelian randomization and colocalization: Review and comparison of approaches

Mendelian randomization and colocalization are two statistical approaches that can be applied to summarized data from genome-wide association studies (GWASs) to understand relationships between traits and diseases. However, despite similarities in scope, they are different in their objectives, imple...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Am J Hum Genet
Prif Awduron: Zuber, Verena, Grinberg, Nastasiya F., Gill, Dipender, Manipur, Ichcha, Slob, Eric A.W., Patel, Ashish, Wallace, Chris, Burgess, Stephen
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2022
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7612737/
https://ncbi.nlm.nih.gov/pubmed/35452592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2022.04.001
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