Combining evidence from Mendelian randomization and colocalization: Review and comparison of approaches

Mendelian randomization and colocalization are two statistical approaches that can be applied to summarized data from genome-wide association studies (GWASs) to understand relationships between traits and diseases. However, despite similarities in scope, they are different in their objectives, imple...

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Bibliografiske detaljer
Udgivet i:Am J Hum Genet
Main Authors: Zuber, Verena, Grinberg, Nastasiya F., Gill, Dipender, Manipur, Ichcha, Slob, Eric A.W., Patel, Ashish, Wallace, Chris, Burgess, Stephen
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2022
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7612737/
https://ncbi.nlm.nih.gov/pubmed/35452592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2022.04.001
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