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Replicative history marks transcriptional and functional disparity in the CD8(+) T cell memory pool

Clonal expansion is a core aspect of T cell immunity. However, little is known with respect to the relationship between replicative history and the formation of distinct CD8(+) memory T cell subgroups. To address this issue, we developed a genetic-tracing approach, termed the DivisionRecorder, that...

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Detalhes bibliográficos
Publicado no:Nat Immunol
Main Authors: Bresser, Kaspar, Kok, Lianne, Swain, Arpit C., King, Lisa A., Jacobs, Laura, Weber, Tom S., Perié, Leïla, Duffy, Ken R., de Boer, Rob J., Scheeren, Ferenc A., Schumacher, Ton N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2022
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7612726/
https://ncbi.nlm.nih.gov/pubmed/35393592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-022-01171-9
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