Assessing CSF ctDNA to Improve Diagnostic Accuracy and Therapeutic Monitoring in Breast Cancer Leptomeningeal Metastasis

PURPOSE: Cerebrospinal fluid (CSF) cytology is the gold standard diagnostic test for breast cancer leptomeningeal metastasis (BCLM), but has impaired sensitivity, often necessitating repeated lumbar puncture to confirm or refute diagnosis. Further, there is no quantitative response tool to assess re...

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Vydáno v:Clin Cancer Res
Hlavní autoři: Fitzpatrick, Amanda, Iravani, Marjan, Mills, Adam, Childs, Lucy, Alaguthurai, Thanussuyah, Clifford, Angela, Garcia-Murillas, Isaac, Van Laere, Steven, Dirix, Luc, Harries, Mark, Okines, Alicia, Turner, Nicholas C., Haider, Syed, Tutt, Andrew N.J., Isacke, Clare M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Association for Cancer Research 2022
Témata:
Precision Medicine and Imaging
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7612501/
https://ncbi.nlm.nih.gov/pubmed/34921020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-21-3017
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