Local Treatment of a Pediatric Osteosarcoma Model with a 4-1BBL Armed Oncolytic Adenovirus Results in an Antitumor Effect and Leads to Immune Memory

Osteosarcoma is an aggressive bone tumor occurring primarily in pediatric patients. Despite years of intensive research, the outcomes of patients with metastatic disease or those who do not respond to therapy have remained poor and have not changed in the last 30 years. Oncolytic virotherapy is beco...

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Enregistré dans:
Détails bibliographiques
Publié dans:Mol Cancer Ther
Auteurs principaux: Martinez-Velez, Naiara, Laspidea, Virginia, Zalacain, Marta, Labiano, Sara, García-Moure, Marc, Puigdelloses, Montse, Marrodan, Lucía, Gonzalez-Huarriz, Marisol, Herrador, Guillermo, de la Nava, Daniel, Ausejo-Mauleon, Iker, Fueyo, Juan, Gomez-Manzano, Candelaria, Patiño-García, Ana, Alonso, Marta M.
Format: Artigo
Langue:Inglês
Publié: American Association for Cancer Research 2022
Sujets:
Models and Technologies
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7612474/
https://ncbi.nlm.nih.gov/pubmed/34965961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-21-0565
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