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Experimental considerations for the assessment of in vivo and in vitro opioid pharmacology

Morphine and other mu-opioid receptor (MOR) agonists remain the mainstay treatment of acute and prolonged pain states worldwide. The major limiting factor for continued use of these current opioids is the high incidence of side effects that result in loss of life and loss of quality of life. The dev...

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Publicat a:Pharmacol Ther
Autors principals: Hill, Rob, Canals, Meritxell
Format: Artigo
Idioma:Inglês
Publicat: 2022
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7612340/
https://ncbi.nlm.nih.gov/pubmed/34256067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2021.107961
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