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Evolution of virus-like protein architecture and genome packaging mechanisms in a repurposed bacterial enzyme
Viruses are ubiquitous pathogens of global impact. Prompted by the hypothesis that their earliest progenitors recruited host proteins for virion formation, we have used stringent laboratory evolution to convert a bacterial enzyme lacking affinity for nucleic acids into an artificial nucleocapsid tha...
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| 出版年: | Science |
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| 主要な著者: | , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2021
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7612296/ https://ncbi.nlm.nih.gov/pubmed/34112695 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.abg2822 |
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