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A compact Cascade-Cas3 system for targeted genome engineering
CRISPR-Cas technologies have provided programmable gene editing tools that have revolutionized research. The leading CRISPR-Cas9 and Cas12a enzymes are ideal for programmed genetic manipulation, however, they are limited for genome-scale interventions. Here, we utilize a Cas3-based system featuring...
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| Publicado no: | Nat Methods |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7611934/ https://ncbi.nlm.nih.gov/pubmed/33077967 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41592-020-00980-w |
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