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Structural Basis of Transcription: RNA Polymerase backtracking and its reactivation
Regulatory sequences or erroneous incorporations during DNA transcription cause RNA polymerase backtracking, and inactivation in all kingdoms of life. Reactivation requires RNA transcript cleavage. Essential transcription factors (GreA/GreB, or TFIIS) accelerate this reaction. We report four cryo-EM...
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| Publicado no: | Mol Cell |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7611809/ https://ncbi.nlm.nih.gov/pubmed/31103420 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.04.029 |
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