Effector differentiation downstream of lineage commitment in ILC1 is driven by Hobit across tissues

Innate lymphoid cells (ILCs) participate in tissue homeostasis, inflammation and early immunity against infection. It is unclear how ILCs acquire effector function, and whether these mechanisms differ between organs. Through multiplexed single-cell mRNA-sequencing we identified cKit(+)CD127(hi)TCF-1...

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Bibliographic Details
Published in:Nat Immunol
Main Authors: Friedrich, Christin, Taggenbrock, Renske L. R. E., Doucet-Ladevèze, Rémi, Golda, Gosia, Moenius, Rebekka, Arampatzi, Panagiota, Kragten, Natasja A. M., Kreymborg, Katharina, de Agüero, Mercedes Gomez, Kastenmueller, Wolfgang, Saliba, Antoine-Emmanuel, Grün, Dominic, van Gisbergen, Klaas P. J. M., Gasteiger, Georg
Format: Artigo
Language:Inglês
Published: 2021
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611762/
https://ncbi.nlm.nih.gov/pubmed/34462601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-021-01013-0
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