Effector differentiation downstream of lineage commitment in ILC1 is driven by Hobit across tissues

Innate lymphoid cells (ILCs) participate in tissue homeostasis, inflammation and early immunity against infection. It is unclear how ILCs acquire effector function, and whether these mechanisms differ between organs. Through multiplexed single-cell mRNA-sequencing we identified cKit(+)CD127(hi)TCF-1...

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Xehetasun bibliografikoak
Argitaratua izan da:Nat Immunol
Egile Nagusiak: Friedrich, Christin, Taggenbrock, Renske L. R. E., Doucet-Ladevèze, Rémi, Golda, Gosia, Moenius, Rebekka, Arampatzi, Panagiota, Kragten, Natasja A. M., Kreymborg, Katharina, de Agüero, Mercedes Gomez, Kastenmueller, Wolfgang, Saliba, Antoine-Emmanuel, Grün, Dominic, van Gisbergen, Klaas P. J. M., Gasteiger, Georg
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2021
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611762/
https://ncbi.nlm.nih.gov/pubmed/34462601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-021-01013-0
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