Impairment of Apoptotic Cell Engulfment by Pyocyanin, A Toxic Metabolite of Pseudomonas Aeruginosa

RATIONALE: Cystic fibrosis lung disease is characterized by accumulation of apoptotic neutrophils, indicating impaired clearance of dying cells. Pseudomonas aeruginosa, the principal microbial pathogen in cystic fibrosis, manipulates apoptosis induction via production of toxic metabolites. Whether t...

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Publicado en:Am J Respir Crit Care Med
Main Authors: Bianchi, Stephen M., Prince, Lynne R., McPhillips, Kathleen, Allen, Lucy, Marriott, Helen M., Taylor, Graham W., Hellewell, Paul G., Sabroe, Ian, Dockrell, David H., Henson, Peter W., Whyte, Moira K.B.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611754/
https://ncbi.nlm.nih.gov/pubmed/17916805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200612-1804OC
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