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Subversion of a Lysosomal Pathway Regulating Neutrophil Apoptosis by a Major Bacterial Toxin, Pyocyanin

Neutrophils undergo rapid constitutive apoptosis that is accelerated following bacterial ingestion as part of effective immunity, but is also accelerated by bacterial exotoxins as a mechanism of immune evasion. The paradigm of pathogen-driven neutrophil apoptosis is exemplified by the Pseudomonas ae...

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Detalhes bibliográficos
Main Authors: Prince, Lynne R., Bianchi, Stephen M., Vaughan, Kathryn M., Bewley, Martin A., Marriott, Helen M., Walmsley, Sarah R., Taylor, Graham W., Buttle, David J., Sabroe, Ian, Dockrell, David H., Whyte, Moira K. B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2262923/
https://ncbi.nlm.nih.gov/pubmed/18292577
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