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Inhibition of neutrophil apoptosis by ATP is mediated by the P2Y(11) receptor

Neutrophils undergo rapid constitutive apoptosis that is delayed by a range of pathogen and host derived inflammatory mediators. We have investigated the ability of the nucleotide ATP, to which neutrophils are exposed both in the circulation and at sites of inflammation, to modulate the lifespan of...

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Autors principals: Vaughan, Kathryn R., Stokes, Leanne, Prince, Lynne R., Meis, Sabine, Kassack, Matthias U., Bingle, Colin D., Sabroe, Ian, Surprenant, Annmarie, Whyte, Moira K.B.
Format: Artigo
Idioma:Inglês
Publicat: 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2292245/
https://ncbi.nlm.nih.gov/pubmed/18056402
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