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Probing Differential Binding Mechanisms of Phenylalanine-Glycine-Rich Nucleoporins by Single-Molecule FRET

Phenylalanine-glycine-rich nucleoporins (FG-Nups) are intrinsically disordered proteins, constituting the selective barrier of the nuclear pore complex. They are highly dynamic under physiological conditions and studying their interaction with nuclear transport receptors (NTRs) is key to understandi...

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Enregistré dans:
Détails bibliographiques
Publié dans:Methods Enzymol
Auteurs principaux: Tan, Piau Siong, Lemke, Edward A.
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611734/
https://ncbi.nlm.nih.gov/pubmed/30471692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2018.08.034
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