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Probing Differential Binding Mechanisms of Phenylalanine-Glycine-Rich Nucleoporins by Single-Molecule FRET

Phenylalanine-glycine-rich nucleoporins (FG-Nups) are intrinsically disordered proteins, constituting the selective barrier of the nuclear pore complex. They are highly dynamic under physiological conditions and studying their interaction with nuclear transport receptors (NTRs) is key to understandi...

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Detalhes bibliográficos
Publicado no:Methods Enzymol
Main Authors: Tan, Piau Siong, Lemke, Edward A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611734/
https://ncbi.nlm.nih.gov/pubmed/30471692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2018.08.034
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