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Decoding myofibroblast origins in human kidney fibrosis

Kidney fibrosis is the hallmark of chronic kidney disease progression, however, currently no antifibrotic therapies exist. This is largely because the origin, functional heterogeneity and regulation of scar-forming cells during human kidney fibrosis remains poorly understood. Here, using single cell...

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Bibliografski detalji
Izdano u:Nature
Glavni autori: Kuppe, Christoph, Ibrahim, Mahmoud M, Kranz, Jennifer, Zhang, Xiaoting, Ziegler, Susanne, Perales-Patón, Javier, Jansen, Jitske, Reimer, Katharina C., Smith, James R., Dobie, Ross, Wilson-Kanamari, John R., Halder, Maurice, Xu, Yaoxian, Kabgani, Nazanin, Kaesler, Nadine, Klaus, Martin, Gernhold, Lukas, Puelles, Victor G., Huber, Tobias B., Boor, Peter, Menzel, Sylvia, Hoogenboezem, Remco M., Bindels, Eric M.J., Steffens, Joachim, Floege, Jürgen, Schneider, Rebekka K, Saez-Rodriguez, Julio, Henderson, Neil C, Kramann, Rafael
Format: Artigo
Jezik:Inglês
Izdano: 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611626/
https://ncbi.nlm.nih.gov/pubmed/33176333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-2941-1
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