Decoding myofibroblast origins in human kidney fibrosis

Kidney fibrosis is the hallmark of chronic kidney disease progression, however, currently no antifibrotic therapies exist. This is largely because the origin, functional heterogeneity and regulation of scar-forming cells during human kidney fibrosis remains poorly understood. Here, using single cell...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Kuppe, Christoph, Ibrahim, Mahmoud M, Kranz, Jennifer, Zhang, Xiaoting, Ziegler, Susanne, Perales-Patón, Javier, Jansen, Jitske, Reimer, Katharina C., Smith, James R., Dobie, Ross, Wilson-Kanamari, John R., Halder, Maurice, Xu, Yaoxian, Kabgani, Nazanin, Kaesler, Nadine, Klaus, Martin, Gernhold, Lukas, Puelles, Victor G., Huber, Tobias B., Boor, Peter, Menzel, Sylvia, Hoogenboezem, Remco M., Bindels, Eric M.J., Steffens, Joachim, Floege, Jürgen, Schneider, Rebekka K, Saez-Rodriguez, Julio, Henderson, Neil C, Kramann, Rafael
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611626/
https://ncbi.nlm.nih.gov/pubmed/33176333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-2941-1
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