Fatty acid chain length drives lysophosphatidylserine dependent immunological outputs

In humans, lysophosphatidylserines (lyso-PSs) are potent lipid regulators of important immunological processes. Given their structural diversity and commercial paucity, here, we report the synthesis of methyl-esters of lyso-PS (Me-lyso-PS), containing medium to very-long chain (VLC) lipid tails. We...

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Bibliographic Details
Published in:Cell Chem Biol
Main Authors: Khandelwal, Neha, Shaikh, Minhaj, Mhetre, Amol, Singh, Shubham, Sajeevan, Theja, Joshi, Alaumy, Balaji, Kithiganahalli Narayanswamy, Chakrapani, Harinath, Kamat, Siddhesh S.
Format: Artigo
Language:Inglês
Published: 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611549/
https://ncbi.nlm.nih.gov/pubmed/33571455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2021.01.008
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