Downregulation of A20 promotes immune escape of lung Adenocarcinomas

Inflammation is a well-known driver of lung tumorigenesis. Tumor cells escape tight homeostatic control by decreasing the expression of the potent anti-inflammatory protein TNFAIP3, also known as A20. Tumor cell intrinsic loss of A20 dramatically enhances lung tumorigenesis and prevents CD8+ T cell...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Sci Transl Med
Main Authors: Breitenecker, Kristina, Homolya, Monika, Luca, Andreea C., Lang, Veronika, Trenk, Christoph, Petroczi, Georg, Mohrherr, Julian, Horvath, Jaqueline, Moritsch, Stefan, Haas, Lisa, Kurnaeva, Margarita, Eferl, Robert, Stoiber, Dagmar, Moriggl, Richard, Bilban, Martin, Obenauf, Anna C., Ferran, Christiane, Dome, Balazs, Laszlo, Viktoria, Győrffy, Balázs, Dezso, Katalin, Moldvay, Judit, Casanova, Emilio, Moll, Herwig P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611502/
https://ncbi.nlm.nih.gov/pubmed/34233950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.abc3911
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados