A Mouse Model to Assess STAT3 and STAT5A/B Combined Inhibition in Health and Disease Conditions

Genetically-engineered mouse models (GEMMs) lacking diseased-associated gene(s) globally or in a tissue-specific manner represent an attractive tool with which to assess the efficacy and toxicity of targeted pharmacological inhibitors. Stat3 and Stat5a/b transcription factors have been implicated in...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Cancers (Basel)
Hlavní autoři: Moll, Herwig P., Mohrherr, Julian, Blaas, Leander, Musteanu, Monica, Stiedl, Patricia, Grabner, Beatrice, Zboray, Katalin, König, Margit, Stoiber, Dagmar, Rülicke, Thomas, Strehl, Sabine, Eferl, Robert, Casanova, Emilio
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6770775/
https://ncbi.nlm.nih.gov/pubmed/31443474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11091226
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky