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Monocytes differentiated into macrophages and dendritic cells in the presence of human IFN‐λ3 or IFN‐λ4 show distinct phenotypes

Human IFN‐λ4 is expressed by only a subset of individuals who possess the ΔG variant allele at the dinucleotide polymorphism rs368234815. Recent genetic studies have shown an association between rs368234815 and different infectious and inflammatory disorders. It is not known if IFN‐λ4 has immunomodu...

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Vydáno v:J Leukoc Biol
Hlavní autoři: De, Manjarika, Bhushan, Anand, Chinnaswamy, Sreedhar
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611425/
https://ncbi.nlm.nih.gov/pubmed/33205487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/JLB.3A0120-001RRR
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