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Cell fate coordinates mechano-osmotic forces in intestinal crypt formation

Intestinal organoids derived from single cells undergo complex crypt-villus patterning and morphogenesis. However, the nature and coordination of the underlying forces remains poorly characterized. Through light-sheet microscopy and large-scale imaging quantification, we demonstrate that crypt forma...

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Detalhes bibliográficos
Publicado no:Nat Cell Biol
Main Authors: Yang, Qiutan, Xue, Shi-Lei, Chan, Chii Jou, Rempfler, Markus, Vischi, Dario, Gutierrez, Francisca Maurer, Hiiragi, Takashi, Hannezo, Edouard, Liberali, Prisca
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611267/
https://ncbi.nlm.nih.gov/pubmed/34155381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-021-00700-2
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