Self-maintaining CD103(+) cancer-specific T cells are highly energetic with rapid cytotoxic and effector responses

Enrichment of CD103(+) tumor-infiltrating T lymphocytes (TILs) is associated with improved outcomes in patients. However, the characteristics of human CD103(+) cytotoxic CD8(+) T cells (CTLs) and their role in tumor control remains unclear. We investigated the features and antitumor mechanisms of CD...

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Udgivet i:Cancer Immunol Res
Main Authors: Hamid, Megat Abd, Colin-York, Huw, Alham, Nasullah Khalid, Browne, Molly, Cerundolo, Lucia, Chen, Ji-Li, Yao, Xuan, Rosendo-Machado, Samara, Waugh, Craig, Maldonado-Perez, David, Bowes, Emma, Verrill, Clare, Cerundolo, Vincenzo, Conlon, Christopher P., Fritzsche, Marco, Peng, Yanchun, Dong, Tao
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611226/
https://ncbi.nlm.nih.gov/pubmed/31771983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-19-0554
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