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Extracellular-regulated protein kinase 5-mediated control of p21 expression promotes macrophage proliferation associated with tumor growth and metastasis

The presence of immunosuppressive macrophages that become activated in the tumor microenvironment constitutes a major factor responsible for tumor growth and malignancy. In line with this knowledge, we report here that macrophage proliferation is a significant feature of advanced stages of cancer. M...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Giurisato, Emanuele, Lonardi, Silvia, Telfer, Brian, Lussoso, Sarah, Risa-Ebrí, Blanca, Zhang, Jingwei, Russo, Ilaria, Wang, Jinhua, Santucci, Annalisa, Finegan, Katherine G., Gray, Nathanael S., Vermi, William, Tournier, Cathy
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611207/
https://ncbi.nlm.nih.gov/pubmed/32561530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-19-2416
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