Targeting cellular senescence based on interorganelle communication, multilevel proteostasis, and metabolic control

Cellular senescence, a stable cell division arrest caused by severe damage and stress, is a hallmark of aging in vertebrates including humans. With progressing age, senescent cells accumulate in a variety of mammalian tissues, where they contribute to tissue aging, identifying cellular senescence as...

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Bibliographic Details
Published in:FEBS J
Main Authors: Cavinato, Maria, Madreiter‐Sokolowski, Corina T., Büttner, Sabrina, Schosserer, Markus, Zwerschke, Werner, Wedel, Sophia, Grillari, Johannes, Graier, Wolfgang F., Jansen‐Dürr, Pidder
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2020
Subjects:
State‐of‐the‐Art Reviews
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611050/
https://ncbi.nlm.nih.gov/pubmed/33200494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.15631
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