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TASL is the SLC15A4-associated adaptor for IRF5 activation by TLR7-9
Toll-like receptors (TLRs) have a crucial role in the recognition of pathogens and initiation of immune responses(1–3). Here we show that a previously uncharacterized protein encoded by CXorf21—a gene that is associated with systemic lupus erythematosus(4,5)—interacts with the endolysosomal transpor...
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| הוצא לאור ב: | Nature |
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2020
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7610944/ https://ncbi.nlm.nih.gov/pubmed/32433612 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-2282-0 |
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