MAIT cell activation augments adenovirus vector vaccine immunogenicity*

Mucosal-associated invariant T (MAIT) cells are innate sensors of viruses and can augment early immune responses and contribute to protection. We hypothesized MAIT cells may have inherent adjuvant activity in vaccine platforms that employ replication-incompetent adenovirus vectors. In mice and human...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Science
Main Authors: Provine, Nicholas M., Amini, Ali, Garner, Lucy C., Spencer, Alexandra J., Dold, Christina, Hutchings, Claire, Reyes, Laura Silva, FitzPatrick, Michael E.B., Chinnakannan, Senthil, Oguti, Blanche, Raymond, Meriel, Ulaszewska, Marta, Troise, Fulvia, Sharpe, Hannah, Morgan, Sophie B., Hinks, Timothy S.C., Lambe, Teresa, Capone, Stefania, Folgori, Antonella, Barnes, Eleanor, Rollier, Christine S., Pollard, Andrew J., Klenerman, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7610941/
https://ncbi.nlm.nih.gov/pubmed/33510029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aax8819
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados