A widespread role for SLC transmembrane transporters in resistance to cytotoxic drugs

Solute Carriers (SLCs) represent the largest family of transmembrane transporters in humans and constitute major determinants of cellular metabolism. Several SLCs have been shown to be required for the uptake of chemical compounds into cellular systems, but systematic surveys of transporter-drug rel...

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Publicado no:Nat Chem Biol
Main Authors: Girardi, Enrico, César-Razquin, Adrián, Lindinger, Sabrina, Papakostas, Konstantinos, Konecka, Justyna, Hemmerich, Jennifer, Kickinger, Stefanie, Kartnig, Felix, Gürtl, Bettina, Klavins, Kristaps, Sedlyarov, Vitaly, Ingles-Prieto, Alvaro, Fiume, Giuseppe, Koren, Anna, Lardeau, Charles-Hugues, Kandasamy, Richard Kumaran, Kubicek, Stefan, Ecker, Gerhard F., Superti-Furga, Giulio
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7610918/
https://ncbi.nlm.nih.gov/pubmed/32152546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-020-0483-3
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