CARMN Loss Regulates Smooth Muscle Cells and Accelerates Atherosclerosis in Mice

RATIONALE: In the microenvironment of atherosclerotic lesions, vascular smooth muscle cells (vSMCs) switch to a dedifferentiated state but the underlying molecular mechanisms driving this switch are not fully understood. Long noncoding RNAs (lncRNAs) are dysregulated during vascular pathology, but r...

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Veröffentlicht in:Circ Res
Hauptverfasser: Vacante, Francesca, Rodor, Julie, Lalwani, Mukesh K., Mahmoud, Amira D., Bennett, Matthew, De Pace, Azzura L., Miller, Eileen, Van Kuijk, Kim, de Bruijn, Jenny, Gijbels, Marion, Williams, Thomas C., Clark, Michael B., Scanlon, Jessica P., Doran, Amanda C., Montgomery, Rusty, Newby, David E., Giacca, Mauro, O’Carroll, Dónal, Hadoke, Patrick W.F., Denby, Laura, Sluimer, Judith C., Baker, Andrew H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7610708/
https://ncbi.nlm.nih.gov/pubmed/33622045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.120.318688
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