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An intramembrane chaperone complex facilitates membrane protein biogenesis

Integral membrane proteins represent approximately 25% of protein-coding genes(1). In eukaryotes, the vast majority of membrane proteins are inserted, modified, and folded at the endoplasmic reticulum (ER)(2). Extensive work over the past several decades has determined how membrane proteins are targ...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Nature
Main Authors: Chitwood, Patrick J., Hegde, Ramanujan S.
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7610463/
https://ncbi.nlm.nih.gov/pubmed/32814900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-2624-y
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