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EMC Is Required to Initiate Accurate Membrane Protein Topogenesis
Mammals encode ∼5,000 integral membrane proteins that need to be inserted in a defined topology at the endoplasmic reticulum (ER) membrane by mechanisms that are incompletely understood. Here, we found that efficient biogenesis of β1-adrenergic receptor (β1AR) and other G protein-coupled receptors (...
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| Publicado no: | Cell |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cell Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6269167/ https://ncbi.nlm.nih.gov/pubmed/30415835 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.10.009 |
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