A carregar...
Senescence as a therapeutically relevant response to CDK4/6 inhibitors
Cyclin-dependent kinases 4 and 6 (CDK4/6) phosphorylate and inhibit retinoblastoma (RB) family proteins. Hyperphosphorylated RB releases E2F transcription factors, activating a transcriptional program that initiates S phase. Due to the critical role that this pathway has in regulating cell cycle pro...
Na minha lista:
| Publicado no: | Oncogene |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7610384/ https://ncbi.nlm.nih.gov/pubmed/32541838 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-1354-9 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|