The T-box Transcription Factor Eomesodermin Governs Hemogenic Competence of Yolk-Sac Mesodermal Progenitors

Extra-embryonic mesoderm (ExM), the earliest cells that traverse the primitive streak (PS), give rise to the endothelium as well as hematopoietic progenitors in the developing yolk-sac (YS). How a specific subset of ExM becomes committed to a hematopoietic fate remains unclear. Here we demonstrate u...

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發表在:Nat Cell Biol
Main Authors: Harland, Luke T.G., Simon, Claire S., Senft, Anna D., Costello, Ita, Greder, Lucas, Imaz-Rosshandler, Ivan, Gottgens, Berthold, Marioni, John C., Bikoff, Elizabeth K., Porcher, Catherine, de Bruijn, Marella, Robertson, Elizabeth J.
格式: Artigo
語言:Inglês
出版: 2021
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7610381/
https://ncbi.nlm.nih.gov/pubmed/33420489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-020-00611-8
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