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Influence of Bile Composition on Membrane Incorporation of Transient Permeability Enhancers

[Image: see text] Transient permeability enhancers (PEs), such as caprylate, caprate, and salcaprozate sodium (SNAC), improve the bioavailability of poorly permeable macromolecular drugs. However, the effects are variable across individuals and classes of macromolecular drugs and biologics. Here, we...

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Detalhes bibliográficos
Publicado no:Mol Pharm
Main Authors: Hossain, Shakhawath, Joyce, Paul, Parrow, Albin, Jõemetsa, Silver, Höök, Fredrik, Larsson, Per, Bergström, Christel A. S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2020
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7610231/
https://ncbi.nlm.nih.gov/pubmed/32960068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.0c00668
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