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Influence of Bile Composition on Membrane Incorporation of Transient Permeability Enhancers

[Image: see text] Transient permeability enhancers (PEs), such as caprylate, caprate, and salcaprozate sodium (SNAC), improve the bioavailability of poorly permeable macromolecular drugs. However, the effects are variable across individuals and classes of macromolecular drugs and biologics. Here, we...

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Bibliografiske detaljer
Udgivet i:Mol Pharm
Main Authors: Hossain, Shakhawath, Joyce, Paul, Parrow, Albin, Jõemetsa, Silver, Höök, Fredrik, Larsson, Per, Bergström, Christel A. S.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2020
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7610231/
https://ncbi.nlm.nih.gov/pubmed/32960068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.0c00668
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