Identification of Theaflavin-3,3’-Digallate as a Novel Zika Virus Protease Inhibitor

Mounting evidence indicates that Zika virus (ZIKV) is closely related to neurological disorders such as microcephaly and Guillain-Barré syndrome. There are currently no effective vaccines and FDA-approved inhibitors against ZIKV infection. The flaviviral heterodimeric serine protease NS2B-NS3 plays...

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Enregistré dans:
Détails bibliographiques
Publié dans:Front Pharmacol
Auteurs principaux: Cui, Xiangling, Zhou, Rui, Huang, Chenchao, Zhang, Rongyu, Wang, Jing, Zhang, Yongxin, Ding, Jiwei, Li, Xiaoyu, Zhou, Jinming, Cen, Shan
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2020
Sujets:
Pharmacology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7609463/
https://ncbi.nlm.nih.gov/pubmed/33192499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.514313
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