Inhibition of SARS-CoV 3C-like Protease Activity by Theaflavin-3,3′-digallate (TF3)

SARS-CoV is the causative agent of severe acute respiratory syndrome (SARS). The virally encoded 3C-like protease (3CL(Pro)) has been presumed critical for the viral replication of SARS-CoV in infected host cells. In this study, we screened a natural product library consisting of 720 compounds for i...

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Main Authors: Chen, Chia-Nan, Lin, Coney P. C., Huang, Kuo-Kuei, Chen, Wei-Cheng, Hsieh, Hsin-Pang, Liang, Po-Huang, Hsu, John T.-A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2005
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1142193/
https://ncbi.nlm.nih.gov/pubmed/15937562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ecam/neh081
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