Kynurenine Pathway of Tryptophan Metabolism in Neuropsychiatric Disorders: Pathophysiologic and Therapeutic Considerations

Under physiological conditions 95% of the ingested essential amino acid tryptophan is metabolized by the kynurenine pathway (KP) to yield the ubiquitous co-enzyme nicotinamide adenine dinucleotide, fulfilling cellular energy require-ments. Importantly, the intermediaries of KP exert crucial effects...

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Bibliographic Details
Published in:Clin Psychopharmacol Neurosci
Main Author: Muneer, Ather
Format: Artigo
Language:Inglês
Published: Korean College of Neuropsychopharmacology 2020
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7609208/
https://ncbi.nlm.nih.gov/pubmed/33124585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.9758/cpn.2020.18.4.507
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