Serum Metabolic Profiles of the Tryptophan-Kynurenine Pathway in the high risk subjects of major depressive disorder

Previous reports have shown that during chronic inflammation, the tryptophan (TRP)-kynurenine (KYN) pathway plays a pivotal role in the onset of depression. The aim of this study was to investigate the characteristics of the serum TRP-KYN pathway metabolite profile in high-risk subjects of major dep...

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Udgivet i:Sci Rep
Main Authors: Sakurai, Masashi, Yamamoto, Yasuko, Kanayama, Noriyo, Hasegawa, Masaya, Mouri, Akihiro, Takemura, Masao, Matsunami, Hidetoshi, Miyauchi, Tomoya, Tokura, Tatsuya, Kimura, Hiroyuki, Ito, Mikiko, Umemura, Eri, (Boku), Aiji Sato, Nagashima, Wataru, Tonoike, Takashi, Kurita, Kenichi, Ozaki, Norio, Nabeshima, Toshitaka, Saito, Kuniaki
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7005270/
https://ncbi.nlm.nih.gov/pubmed/32029791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-58806-w
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