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Human neural stem cells improve early stage stroke outcome in delayed tissue plasminogen activator-treated aged stroke brains
INTRODUCTION: Clinically, significant stroke injury results from ischemia-reperfusion (IR), which induces a deleterious biphasic opening of the blood-brain barrier (BBB). Tissue plasminogen activator (tPA) remains the sole pharmacological agent to treat ischemic stroke. However, major limitations of...
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| Veröffentlicht in: | Exp Neurol |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7609039/ https://ncbi.nlm.nih.gov/pubmed/32147438 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2020.113275 |
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