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Human neural stem cells improve early stage stroke outcome in delayed tissue plasminogen activator-treated aged stroke brains

INTRODUCTION: Clinically, significant stroke injury results from ischemia-reperfusion (IR), which induces a deleterious biphasic opening of the blood-brain barrier (BBB). Tissue plasminogen activator (tPA) remains the sole pharmacological agent to treat ischemic stroke. However, major limitations of...

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Bibliografiske detaljer
Udgivet i:Exp Neurol
Main Authors: Boese, Austin C., Eckert, Auston, Hamblin, Milton H., Lee, Jean-Pyo
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7609039/
https://ncbi.nlm.nih.gov/pubmed/32147438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2020.113275
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